Recommend individuals to dilute Just about every dose of DEMEROL oral solution in one-fifty percent glass of drinking water since the undiluted Remedy may well exert a slight topical anesthetic effect on mucous membranes.
Although each medicine are taken orally, they have got different dosing regimens and strengths associated with a particular prescription.
For clinically important respiratory or circulatory despair secondary to meperidine overdose, administer an opioid antagonist. Because the duration of opioid reversal is expected being under the length of motion of meperidine in DEMEROL Tablets and Oral Answer, diligently observe the individual till spontaneous respiration is reliably reestablished. When the reaction to an opioid antagonist is suboptimal or only temporary in nature, administer additional antagonist as directed because of the item’s prescribing data.
five.15 Greater Hazard of Seizures in Patients with Seizure Problems The meperidine in DEMEROL Tablets and Oral Remedy might improve the frequency of seizures in people with seizure Conditions, and should improve the possibility of seizures occurring in other scientific configurations connected to seizures. If dosage is escalated significantly over proposed amounts on account of tolerance growth, seizures may occur in people today and not using a record of seizures Diseases.
DEMEROL Injection is indicated for the management of discomfort severe ample to require an opioid analgesic and for which substitute treatments are inadequate.
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5.12 Critical Hypotension DEMEROL Tablets and Oral Answer might induce significant hypotension including orthostatic hypotension and syncope in ambulatory patients. You can find elevated threat in patients whose potential to take care of blood pressure has currently been compromised by a reduced blood volume or concurrent administration of specified CNS depressant prescription drugs (e.
Don't forget, keep this and all other medicines out with the attain of kids, in no way share your medicines with Many others, and use codeine only for the indication prescribed.
Daily life-Threatening Respiratory Despair Tell patients of the chance of lifestyle-threatening respiratory melancholy, such as data that the risk is best when setting up DEMEROL Tablets or Oral Resolution or in the event the dosage is increased, and that it could possibly take place even at proposed dosages.
In this sort of people today, reduced doses are a good idea. Some adverse reactions in ambulatory patients could be alleviated In the event the patient lies down.
Swallow the combination right away. Usually do not chew the mixture, and don't put it aside for long term use. Consume a glass of liquid immediately after Every single dose.
Expecting or intending to turn into Expecting. Prolonged usage of DEMEROL Tablets and Oral Alternative during pregnancy may cause withdrawal signs and symptoms in your newborn baby that could be lifetime-threatening if not regarded and taken care of.
DEMEROL Injection exposes individuals along with click here other buyers into the dangers of opioid dependancy, abuse, and misuse, which may lead to overdose and Demise.
professional Health care options. This facts is generalized rather than supposed as specific health-related tips.